Barn og ungdom Barn less than 18 år skal ikke ta dette legemidlet. Andre legemidler og Modiodal: Snakk med lege eller apotek dersom du bruker, nylig har brukt eller planlegger å bruke andre legemidler. Modiodal og visse andre legemidler kan påvirke hverandre, og legen din kan trenge å justere dosene du tar.
Du merker endring i din mentale helse eller velvære. Tegnene kan inkludere: humørsvingninger eller unormale tanker
Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.
Modafinil cuts down extreme sleepiness due to narcolepsy along with other sleep Problems, like periods of stopped breathing through slumber (obstructive rest apnea).
Modafinil isn't however enough to become advisable for these healthcare situations until good facts can be found. It could be perfect to conduct large RCTs in MS and PD investigating the effect of modafinil on either fatigue or sleepiness and sleep Problems needs to be excluded as a major confounder by polysomnography in these research.
The internet site of action mediating this effect hasn't yet been elucidated, and There are a selection of plausible intracellular targets which we investigate below that would reveal both equally modafinil’s stimulant results, neuroprotective effects, and perhaps its results being a therapeutic Device in addiction.
Examine the Medication Information supplied by your pharmacist before you start employing modafinil and each time you obtain a refill. If you have any issues, check with your doctor or pharmacist.
Modafinil kan forbedre din narkolepsi og redusere sannsynligheten for at du vil oppleve søvnanfall, Gentlemen det kan fortsatt finnes andre måter du kan forbedre din tilstand på, og legen din vil gi deg råd. Les avsnitt two. Hva du må vite før du bruker Modiodal Bruk ikke Modiodal dersom du er allergisk overfor modafinil eller noen av de andre innholdsstoffene i dette legemidlet (listet opp i avsnitt 6)
Kontakt nærmeste legevakt, lege eller apotek umiddelbart. Ta med deg dette pakningsvedlegget og eventuelle ubrukte tabletter. Dersom du har glemt å ta Modiodal Dersom du glemmer å ta legemidlet ditt, ta neste dose til vanlig tid. Du skal ikke ta en dobbelt dose som erstatning for en glemt dose. Spør lege eller apotek dersom du har noen spørsmål om bruken av dette legemidlet. Legemiddelfoto Modiodal «Teva» tabletter a hundred mg
Question about reliable kinds of non-hormonal start Manage although employing this medication and for two months after the very last dose. In the event you grow to be Expecting, check with your medical doctor instantly with regards to the risks and benefits of this medication.
Stone et al (2002) showed which the α1A adrenergic receptor antagonist WB4101 along with the α1D antagonist BMY7378 had minimal impact on the increase in motor activity attributable to modafinil, but terazosin, which blocks α1A, α1D, and α1B receptors considerably attenuated this outcome. Moreover, modafinil had extremely small effects on gross motion in α1B receptor knockout mice.
Modafinil er klassifisert som et reseptpliktig legemiddel. Det betyr at du må ha resept for å kunne kjøpe dette på apoteket. Ettersom modafinil ikke er klassifisert som narkotika er det heller ikke straffbart å gi bort din egen medisin til andre som ikke selv har resept, Males det er likevel gode grunner til at du aldri bør gjøre det. Medisinen er skrevet ut til deg
Modafinil was to start with accredited in the United States in December 1998 to be used in narcolepsy and subsequently in January 2004 for use in OSA and SWD. This text reviews the literature on modafinil (pharmacology, pharmacokinetics, efficacy, tolerability, and abuse possible), with emphasis on utilization of modafinil in the therapy of too much sleepiness in website individuals with OSA, SWD, and narcolepsy.
It had been discovered that modafinil was weakly selective for that dopamine transporter, binding to this cell-membrane protein and in no way to every other receptors analyzed. They had been skeptical that modafinil may possibly act by blocking this transporter, and so they identified that modafinil has much more strong behavioral consequences than some molecules that bind that has a Significantly bigger affinity for the dopamine reuptake transporter.